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Image Search Results
Journal: Balkan Medical Journal
Article Title: Comparison of Immune Checkpoint Molecule Expression in Different Years of House Dust Mite Subcutaneous Immunotherapy on CD4 + T and Treg Cells in Children with Allergic Rhinitis
doi: 10.4274/balkanmedj.galenos.2024.2024-6-19
Figure Lengend Snippet: Plasma levels of soluble PD-1, CTLA-4, TIM-3, TIGIT, and LAG-3. Box and violin graphs illustrating the plasma levels of soluble PD-1, CTLA-4, TIM-3, TIGIT, and LAG-3. Each data point represents the ELISA results of a single donor. Median values are indicated by a horizontal line; differences between the groups were analyzed using the Mann-Whitney U test (* p ≤ 0.05 and ** p ≤ 0.01). PD-1, programmed cell death protein-1; CTLA-4, cytotoxic T lymphocyte-associated antigen 4; TIM-3, T cell immunoglobulin and mucin domain containing molecule-3; TIGIT, T cell Immunoreceptor with Immunoglobulin and Immunoreceptor Tyrosine-based Inhibitory Motif; LAG-3, lymphocyte activation gene-3; HDM-SCIT, house dust mite subcutaneous immunotherapy; ICP, immune checkpoint.
Article Snippet: Human soluble PD-1, CTLA-4, TIM-3,
Techniques: Enzyme-linked Immunosorbent Assay, MANN-WHITNEY, Activation Assay